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Bach - drug study question
Topic Started: Jun 7 2006, 03:47 PM (112 Views)
dolmansaxlil
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HOLY CARP!!!
I'm wondering if you could help me. When I was pregnant and then when I was nursing Liam, I was put on Verapamil to control supraventricular tachycardia (a condition I had before pregnancy. It was, at one time, controlled with atenolol, but I had been off meds for awhile before getting pregnant. The SVT got bad when I got pregnant).

I was prescribed the med by an internist that specialized in women's health at Mt. Sinai hospital in Toronto. At the time, she was involved with a study of that drug involving the safety of the medication during pregnancy and breastfeeding, and I participated in the study (was contacted several months after Liam was born for follow-up, etc).

I'm curious if it's possible to find the results of that study. I had Liam in December of 2001. Any thoughts?
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bachophile
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HOLY CARP!!!
did a quick search and nothing published recently on this subject so if there is a study, it hasn't been published yet.

if it was in a clinical trial, im sure u can get the number of the trial and then check it out online.

im attaching this link which is a review on the subject out of holland in 2001.

http://eurheartj.oxfordjournals.org/cgi/reprint/22/6/458

(verapamil is a class IV drug)
"I don't know much about classical music. For years I thought the Goldberg Variations were something Mr. and Mrs. Goldberg did on their wedding night." Woody Allen
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George K
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Finally
bachophile
Jun 7 2006, 08:23 PM
did a quick search and nothing published recently on this subject so if there is a study, it hasn't been published yet.

I'm glad that it wasn't my idiocy that prevented me from finding it. A Pubmed search only yielded about 8 articles - none of them relevant.
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Nothing is as effective as homeopathy.

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bachophile
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HOLY CARP!!!
actually george is better equipped to discuss this.

i dont know sh1t from shinola when it comes to heart meds...
"I don't know much about classical music. For years I thought the Goldberg Variations were something Mr. and Mrs. Goldberg did on their wedding night." Woody Allen
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George K
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Finally
Thanks for the complement, but it's undeserved. The whole subject of maternal drugs and their fo(e)tal effects is a Pandora's box. There could be thousands of pregnant women with no problem in their pregnancies and babies. But, it only takes one...

Beta blockers (such as atenolol) have their share of problems:

Can Pregnant Women Take Beta-Blockers?

Use of beta-blockers during pregnancy may cause slowed heart rate, low blood sugar, and low blood pressure in the baby. Women should inform their doctor if they are trying to become pregnant or become pregnant while on beta-blockers.

Some beta-blockers can pass to the infant through breast milk, causing low blood pressure, difficulty breathing, or slowed heart rate in the baby. Others can slow the flow of breast milk. Alternative feeding methods may need to be used.


However, another source says that it's what stage of pregnancy the drug is given in:

n conclusion, atenolol should be avoided in the early stages of pregnancy and given with caution at the later stages, as it is associated with fetal growth retardation, which is related to duration of treatment.

This study only looked at 78 women - a woefully small sample. Hard to draw any conclusions.

Verapamil is in the FDA pregnancy category C. This means that it is not known whether verapamil will be harmful to an unborn baby.

In general, the less you take in pregnancy, the better off you are.
A guide to GKSR: Click

"Now look here, you Baltic gas passer... "
- Mik, 6/14/08


Nothing is as effective as homeopathy.

I'd rather listen to an hour of Abba than an hour of The Beatles.
- Klaus, 4/29/18
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dolmansaxlil
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HOLY CARP!!!
Thanks to both of you.

My internist wasn't thrilled with the idea of atenolol during pregnancy, which is why she went with verapamil. She wasn't thrilled with that either, but with my heartrate (On a 72 hour monitor, I topped out at 240bpm and stayed there for about 3 hours), she was more concerned about controlling the SVT.

I'm not overly worried about it - Liam is fine, and there were no problems during pregnancy or afterwards. They did a few non-routine scans of his heart after birth just to make sure, and there was nothing abnormal. My dad and grandfather also have the weird heart issues I have, so even if he comes up with that later in life, I don't think I can blame the drug.

I saw a news report today saying that some heart meds for high blood pressure (which is what I've always been put on, unfortunately, considering I already have LOW blood pressure) have undergone recent studies that say they are worse in the first trimester than previously thought, which is what got me thinking.

Thanks for taking a look - I was just curious if anything had been published.
"Your first 10,000 photographs are your worst." ~ Henri Cartier-Bresson

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George K
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Finally
dolmansaxlil
Jun 7 2006, 09:25 PM
with my heartrate (On a 72 hour monitor, I topped out at 240bpm and stayed there for about 3 hours)

:hair: :hair: :hair: :hair: :hair: :hair:

Every time I see you looking my way,
Baby, baby, can't you hear my heartbeat ?
In the park or walking down the high way,
Baby, baby, can't you hear my heartbeat ?
And when you move up closer to me
I get a feeling that's oo-wee.
Can't you hear the pounding of my heartbeat
'Cause you're the one I love, you're the one I love.
When I feel you put your arms around me,
Baby, baby, can't you hear my heartbeat ?
Then I'm glad, I'm mighty glad you found me,
Baby, baby, can't you hear my heartbeat ?
And when you asked me to meet your ma
I knew that baby we'd be goin' far.
Can't you hear the pounding of my heartbeat
'Cause you're the one I love, you're the one I love.
All my friends are crying out to meet you,
Baby, baby, can't you hear my heartbeat ?
Now's the time to go and see the preacher,
Baby, baby, can't you hear my heartbeat ?
Now wedding bells are going to chime
And baby, baby, you're gonna be mine.
Can't you hear the pounding of my heartbeat
'Cause you're the one I love, you're the one I love.
Baby, baby, can't you hear my heartbeat ?
A guide to GKSR: Click

"Now look here, you Baltic gas passer... "
- Mik, 6/14/08


Nothing is as effective as homeopathy.

I'd rather listen to an hour of Abba than an hour of The Beatles.
- Klaus, 4/29/18
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ivorythumper
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I am so adjective that I verb nouns!
George K
Jun 7 2006, 07:30 PM
dolmansaxlil
Jun 7 2006, 09:25 PM
with my heartrate (On a 72 hour monitor, I topped out at 240bpm and stayed there for about 3 hours)

:hair: :hair: :hair: :hair: :hair: :hair:


Baby, baby, can't you hear my heartbeat ?

It must sound like a snare drum.
The dogma lives loudly within me.
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dolmansaxlil
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HOLY CARP!!!
Yeah, it's a bit quick, no? Luckily, it doesn't get up that high any more. My resting pulse is about 75, and when I have an "attack", these days it usually gets up to about 160 or so. It's been worse the past few months than it has been in quite awhile, so I've been looking into how to manage it. The drug option doesn't work well for me, because my BP tends to fall low on the low side (around 90 or 100 over 60) so being on most of these drugs makes me feel awful all the time and lowers my blood pressure further. I've basically run out of options, short of having them go in and zap my heart with electricity - something I'd like to avoid.
"Your first 10,000 photographs are your worst." ~ Henri Cartier-Bresson

My Flickr Photostream


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Jolly
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Geaux Tigers!
Quote:
 
(On a 72 hour monitor, I topped out at 240bpm and stayed there for about 3 hours), she was more concerned about controlling the SVT.


I'm no doc, but the first comment that comes to mind is "Holy Sh*t, Batman!".
The main obstacle to a stable and just world order is the United States.- George Soros
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